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Artificial DNA Created April 20, 2012

Posted by Metabiological in Beyond Earth, Genetics.
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In what appears to be a first scientists have created the first synthetic genetic material that can store information and evolve in a similar way to DNA.

Researchers at the MRC Laboratory of Molecular Biology, in Cambridge, developed chemical procedures to turn DNA and RNA, the molecular blueprints for all known life, into six alternative genetic polymers called XNAs.

The process swaps the deoxyribose and ribose (the “d” and “r” in DNA and RNA) for other molecules. It was found the XNAs could form a double helix with DNA and were more stable than natural genetic material.

Cool news by anyone’s standard.

I will however take issue with one things stated by the authors.

“There is nothing Goldilocks about DNA and RNA,” Holliger told Science. “There is no overwhelming functional imperative for genetic systems or biology to be based on these two nucleic acids.”

That is overstepping bounds to me.   While this has certainly proved the possibility of other molecules forming the basis of genetic material it says nothing about the probability of said molecules actually forming on their own.  As of right now the only truly concrete thing we can say is that despite a very long time to try out different options the only type of genetic material to evolve are DNA and RNA.  Their prevalence, and the lack of any competitors, are the only evidence we have for how successful different types of genetic material are.  DNA may no longer be the only possible configuration but it still may be the most likely one and therefore the most likely basis for life on other worlds.    Far more work needs to be done in order to knock DNA off it’s pedestal.

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